Open access, reproducible science — run by a nonprofit.

We operate community-driven journals and tools that accelerate trustworthy research in drug discovery, development, and safety. No paywalls. Transparent review. Data and code required.

What we do
  • Publish rigorously reviewed, open science across three journals
  • Promote reproducibility via code/data requirements and checklists
  • Pilot community review, registered reports, and open metrics

Our Journals

Open Access
Toxicology

Toxicity Research

Open reports on toxicology methods, datasets, and translational insights.

Visit tr.openfreescience.org
Open Access
AI/ML

AI in Drug Discovery & Development

Methods and applications spanning target ID, molecular design, PK/PD, and trials.

Visit aidd.openfreescience.org

Our Mission

Advance scientific progress by removing barriers to reading, reviewing, and reusing research. We promote open licensing, transparent peer review, and strong reproducibility standards.

  • CC BY 4.0 licensing
  • Mandatory code/data availability statements
  • Open reviewer reports (opt-in) and registered reports

Impact (sample figures)

We share transparent, field-relevant metrics—not paywalled impact factors.

3
active journals
92%
submissions with reproducibility checklists
18 days
median time to first decision

Programs

Open Review & Registered Reports

Authors can opt into publishing reviewer reports and responses. We also support registered reports to reduce publication bias and p-hacking.

Reproducibility & FAIR

Templates and checklists ensure code, data, and model cards are shared under FAIR principles—Findable, Accessible, Interoperable, Reusable.

Support Open Free Science

We’re a nonprofit. Donations fund hosting, editorial infrastructure, community grants, and APC waivers for under-resourced authors.

Donate Contact

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Quarterly news on calls for papers, special issues, and tools.